It's never a good thing when a building burns down. The best case scenario is no people are hurt as stuff can always be replaced. However, one Midwest building burnt down and the "stuff" was very unique including a limousine and a Lamborghini kit car.
Most of the abandoned Missouri locations I've shared are not places you should ever try to go to. However, this more than 150-year-old abandoned Missouri mine is one you can and should visit if mining history is something you're interested in.